Ghost 2003 is a DOS program and NEVER should be Installed on any HD, let alone Vista. In spite of the GUI, Ghost will only run in DOS.
I've been running it from a boot floppy for ten years now, through many upgrades and versions, but Ghost 2003, build 793 is still my favorite.
You also can't move Ghost Image files around like pictures. Restore will want to find them where Ghost put them, not somewhere else.
As for booting up with a Ghost 2003 boot floppy or CD and doing Ghost backups and restores, in XP or Vista.... no problem, I do it all the time.
Good Luck,
The Doctor