WELL, it sounds like the USB port driver chip is blown.
But all is not lost.
You can buy a PCI USB expansion card and plug it into a spare PCI slot, if you have one.
If that works, you can even run a USB hub off of one of the ports on that card.
Good Luck,
The Doctor
PS: The USB ports on my mobo are alive and well, I still have a PCI USB expansion card for five extra USB ports. It comes in handy.